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Updated: Aug 15, 2026

Reliable Mechanochemistry: Protocols for Reproducible Outcomes of Neat and Liquid Assisted Ball-mill Grinding Experiments
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Published on: January 23, 2018

Reinventing the Corey-Fuchs Reaction under Ball Milling Conditions: A Mechanochemical Pathway to Bromoalkynes

Barbara Kaczmarek1, Ireneusz Kownacki1,2, Dawid Frąckowiak2

  • 1Faculty of Chemistry, Adam Mickiewicz University, Poznań 61-614, Poland.

ACS Omega
|August 14, 2026
PubMed
Summary

The Corey-Fuchs reaction is adapted for solvent-free mechanochemical synthesis using ball-milling. This greener approach efficiently produces bromoalkynes from aldehydes, offering improved sustainability.

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