Piperazine-1,4-diium bis-(perchlorate) dihydrate

Area of Science:

• Crystallography
• Chemical structure analysis
• Hydrogen bonding

Background:

• Piperazine derivatives are important in medicinal chemistry.
• Understanding the solid-state structure of protonated amines is crucial for predicting their properties.

Purpose of the Study:

• To determine the crystal structure of the diprotonated piperazine compound C(4)H(12)N(2)·2ClO(4)·2H(2)O.
• To analyze the hydrogen bonding interactions within the crystal lattice.

Main Methods:

• Single-crystal X-ray diffraction was used to elucidate the crystal structure.
• Analysis of bond lengths, angles, and intermolecular interactions was performed.

Main Results:

• The asymmetric unit contains half a piperazinediium cation, one perchlorate anion, and one water molecule.
• The diprotonated piperazine ring adopts a chair conformation.
• A three-dimensional network is formed through intermolecular N-H⋯O and O-H⋯O hydrogen bonds.

Conclusions:

• The crystal structure reveals the specific arrangement of diprotonated piperazine cations, perchlorate anions, and water molecules.
• The hydrogen bonding network plays a significant role in stabilizing the crystal structure.