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Updated: Jun 1, 2026

Microwave-Assisted Preparation of 1-Aryl-1H-pyrazole-5-amines
Published on: June 23, 2019
1,3-Diphenyl-1H-pyrazole-4-carbaldehyde
Abstract:
There are four mol-ecules in the asymmetric unit of the title compound, C(16)H(12)N(2)O. The dihedral angle between the phenyl rings in the mol-ecules are 22.2 (2), 22.4 (2), 25.1 (3) and 41.9 (2)°. In the crystal, mol-ecules form dimers due to inter-molecular C-H⋯O hydrogen bonds, which result in one R(2) (2)(10) and two R(2) (1)(7) ring motifs. Weak aromatic π-π stacking [centroid-centroid separation = 3.788 (3) Å] and C-H⋯π inter-actions may also consolidate the packing.
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