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Updated: Jun 1, 2026
Multi-Scale Modification of Metallic Implants With Pore Gradients, Polyelectrolytes and Their Indirect Monitoring In vivo
Published on: July 1, 2013
In vivo osseointegration of nano-designed composite coatings on titanium implants
Sybille Facca1, Debrupa Lahiri, Florence Fioretti
1Plasma Forming Lab and Nanomechanics and Nanotribology Lab, Department of Mechanical and Materials Engineering, Florida International University, Miami, Florida 33174, United States.
Abstract:
This is the first in vivo study of plasma-sprayed carbon nanotube (CNT)-reinforced hydroxyapatite (HA) coating on titanium implants embedded in rodents' bone. No adverse effect or cytotoxicity of CNT addition on bone tissues and cells was observed. Normal bone growth was observed around HA-CNT-coated implants. CNT addition induces higher osseointegration as compared to HA. Elastic modulus of new bone was compared with the modulus of HA-CNT/bone interface to understand the mechanical integrity of the implant.
