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Implementation of Non-invasive Point of Care Transient Elastography for Evaluation of Liver Disease in Pediatric Populations with Cystic Fibrosis
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Transient creatine phosphokinase elevations in children: a single-center experience

Sebastien Perreault1, Ala Birca, Dominique Piper

  • 1Division of Neurology, Department of Pediatrics, Sainte-Justine Hospital, Montreal, Quebec, Canada. sebperreault@hotmail.com

The Journal of Pediatrics
|May 20, 2011
PubMed

Insights

Pediatric rhabdomyolysis causes vary, including viral myositis, trauma, and surgery. Most childhood rhabdomyolysis cases are benign and do not recur.

Area of Science:

  • Pediatric Nephrology
  • Neurology
  • Genetics

Background:

  • Rhabdomyolysis in children presents diverse etiologies.
  • Understanding these causes is crucial for diagnosis and management.
  • Pediatric rhabdomyolysis differs from adult presentations.

Purpose of the Study:

  • To investigate the causes and progression of rhabdomyolysis in pediatric patients.
  • To analyze the spectrum of rhabdomyolysis etiologies in a pediatric population.

Main Methods:

  • Retrospective study conducted at a tertiary care pediatric hospital.
  • Data collected from 2001 to 2002 for patients in outpatient clinics, emergency departments, or admitted.
  • Standardized case report forms used to gather patient chart data.

Main Results:

  • 130 pediatric patients with rhabdomyolysis were analyzed.
  • Common causes included viral myositis (22.3%), trauma (18.4%), and surgery (18.4%).
  • Metabolic myopathy was rare (0.8%), and 13.1% had no definitive diagnosis.

Conclusions:

  • Pediatric rhabdomyolysis has varied causes distinct from adults.
  • The condition is typically benign and non-recurrent in children.
  • Rhabdomyolysis as an initial symptom of metabolic myopathy is infrequent.
Abstract

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