Transient creatine phosphokinase elevations in children: a single-center experience.
Sebastien Perreault1, Ala Birca, Dominique Piper
1Division of Neurology, Department of Pediatrics, Sainte-Justine Hospital, Montreal, Quebec, Canada. sebperreault@hotmail.com
The Journal of Pediatrics
|May 20, 2011
Summary
Pediatric rhabdomyolysis causes vary, including viral myositis, trauma, and surgery. Most childhood rhabdomyolysis cases are benign and do not recur.
Area of Science:
- Pediatric Nephrology
- Neurology
- Genetics
Background:
- Rhabdomyolysis in children presents diverse etiologies.
- Understanding these causes is crucial for diagnosis and management.
- Pediatric rhabdomyolysis differs from adult presentations.
Purpose of the Study:
- To investigate the causes and progression of rhabdomyolysis in pediatric patients.
- To analyze the spectrum of rhabdomyolysis etiologies in a pediatric population.
Main Methods:
- Retrospective study conducted at a tertiary care pediatric hospital.
- Data collected from 2001 to 2002 for patients in outpatient clinics, emergency departments, or admitted.
- Standardized case report forms used to gather patient chart data.
Main Results:
- 130 pediatric patients with rhabdomyolysis were analyzed.
- Common causes included viral myositis (22.3%), trauma (18.4%), and surgery (18.4%).
- Metabolic myopathy was rare (0.8%), and 13.1% had no definitive diagnosis.
Conclusions:
- Pediatric rhabdomyolysis has varied causes distinct from adults.
- The condition is typically benign and non-recurrent in children.
- Rhabdomyolysis as an initial symptom of metabolic myopathy is infrequent.
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