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10B concentration evaluation in autoradiography images by optical density measurements

A Portu1, G Saint Martin, D Brandizzi

  • 1Centro Atómico Constituyentes (CAC), Comisión Nacional de Energía Atómica (CNEA), San Martín, Buenos Aires, Argentina. portu@cnea.gov

Applied Radiation and Isotopes : Including Data, Instrumentation and Methods for Use in Agriculture, Industry and Medicine
|May 20, 2011
PubMed

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Difference from Background: Limit of Detection01:05

Difference from Background: Limit of Detection

The limit of detection (LOD) is the smallest amount of analyte that can be distinguished from the background noise. The LOD value corresponds to the concentration at which the analyte signal is three times larger than the standard deviation of the blank signal. Below this value, the analyte signal cannot be differentiated from the background noise. It is calculated by dividing the calibration slope by 3 times the standard deviation of the blank signals.
The LOD indicates the presence or absence...