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Free and Cued Selective Reminding Test: an Italian normative study.

P Frasson1, R Ghiretti, E Catricalà

  • 1Department of Neurology and Neurorehabilitation, San Raffaele Turro, Vita-Salute University and San Raffaele Scientific Institute, Milan, Italy.

Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
|May 20, 2011
PubMed
Summary
This summary is machine-generated.

This study provides normative data for an Italian version of the Free and Cued Selective Reminding Test (FCSRT). This test is crucial for diagnosing Alzheimer's dementia by assessing specific episodic memory impairments.

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Area of Science:

  • Neuroscience
  • Psychology
  • Gerontology

Background:

  • Episodic memory impairment is a key diagnostic criterion for Alzheimer's dementia.
  • New research criteria emphasize memory deficits unresponsive to cues or recognition, defining prodromal Alzheimer's disease.
  • The Free and Cued Selective Reminding Test (FCSRT) specifically assesses these core memory deficits.

Purpose of the Study:

  • To establish normative data for an Italian version of the FCSRT.
  • To provide reference scores for healthy Italian adults across different age, sex, and education levels.
  • To facilitate the accurate diagnosis of Alzheimer's dementia and its prodromal stages.

Main Methods:

  • Administered an Italian version of the FCSRT using 12 pictorial stimuli (living and non-living domains).
  • Collected data from 227 healthy Italian adults with diverse demographics.
  • Derived six key performance scores: immediate free recall (IFR), immediate total recall (ITR), delayed-free recall (DFR), delayed total recall (DTR), Index of Sensitivity of Cueing (ISC), and number of intrusions.

Main Results:

  • Age significantly influenced immediate free recall (IFR) and delayed-free recall (DFR), with older adults scoring lower.
  • Higher education levels and female gender were associated with better immediate free recall (IFR) performance.
  • Adjusted scores were computed to establish inferential cutoff and equivalent scores for diagnostic use.

Conclusions:

  • The Italian FCSRT provides reliable normative data for assessing episodic memory deficits in Alzheimer's dementia.
  • Age, education, and gender are important demographic factors influencing FCSRT performance in healthy adults.
  • This study supports the use of the FCSRT for identifying core memory impairments in prodromal Alzheimer's disease.