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Updated: Jun 1, 2026
Using a 1064-nm Picosecond Neodymium-Doped Yttrium Aluminum Garnet Laser for Periorbital Hyperpigmentation
Published on: May 23, 2025
[Treatment of mucosal vascular malformations with variable-pulse neodymium:yttrium-aluminum-garnet laser]
A Nuño-González1, E Naz-Villalba, F J Vicente-Martín
1Unidad de Dermatología, Hospital Universitario Fundación de Alcorcón, Madrid, Spain. anuno@fhalcorcon.es
Background And Objectives:
Treatment of mucosal vascular lesions is a challenge for dermatologists, although various approaches have proven efficacy, including surgery, sclerotherapy, intralesional injection of corticosteroids, transfixion, and laser therapy. The aim of this study was to describe the results of treatment with neodymium:yttrium-aluminum-garnet (Nd:YAG) laser in 11 patients with venous malformations and varicosities.
Patients And Methods:
We describe the use of variable-pulse Nd:YAG to treat venous malformations or varicosities in the oral or genital mucosa of 8 women and 3 men seen in our hospital over a 1-year period.
Results:
The following laser parameters were used: wavelength, 1064 nm; fluence, 100 to 200J/cm(2); spot diameter, 3 to 5mm; and pulse duration, 30 to 65 ms. The size of the lesions ranged from 5 to 30 mm. In all cases, a clearance of 75% to 100% was achieved in a single session with excellent healing and no significant side effects.
Conclusions:
Given its efficacy and ease of use, Nd:YAG may become a treatment of choice for mucosal vascular lesions. Comparative studies are now required to assess its potential superiority over other treatment options.
