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Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses
Published on: August 30, 2018
Antibiotics for URTI and UTI -- prescribing in Malaysian primary care settings
Cheong Lieng Teng1, Seng Fah Tong, Ee Ming Khoo
1Department of Family Medicine, International Medical University, Negeri Sembilan, Malaysia. tengcl@gmail.com
Background:
Overprescription of antibiotics is a continuing problem in primary care. This study aims to assess the antibiotic prescribing rates and antibiotic choices for upper respiratory tract infections (URTI) and urinary tract infections (UTI) in Malaysian primary care.
Method:
Antibiotic prescribing data for URTI and UTI was extracted from a morbidity survey of randomly selected primary care clinics in Malaysia.
Results:
Analysis was performed of 1,163 URTI and 105 UTI encounters. Antibiotic prescribing rates for URTI and UTI were 33.8% and 57.1% respectively. Antibiotic prescribing rates were higher in private clinics compared to public clinics for URTI, but not for UTI. In URTI encounters, the majority of antibiotics prescribed were penicillins and macrolides, but penicillin V was notably underused. In UTI encounters, the antibiotics prescribed were predominantly penicillins or cotrimoxazole.
Discussion:
Greater effort is needed to bring about evidence based antibiotic prescribing in Malaysian primary care, especially for URTIs in private clinics.
Insights
Antibiotic prescribing for upper respiratory tract infections (URTI) and urinary tract infections (UTI) in Malaysian primary care shows high rates, particularly in private clinics for URTI. Evidence-based prescribing needs improvement, especially for URTIs.
Area of Science:
- Infectious Diseases
- Public Health
- Pharmacology
Background:
- Antibiotic overprescription is a significant issue in primary healthcare settings.
- This study addresses the critical need to evaluate antibiotic use for common infections.
Purpose of the Study:
- To assess antibiotic prescribing rates and drug selection for upper respiratory tract infections (URTI) and urinary tract infections (UTI).
- To identify patterns and potential areas for improvement in Malaysian primary care.
Main Methods:
- Utilized data from a morbidity survey of randomly selected primary care clinics across Malaysia.
- Analyzed antibiotic prescribing patterns for 1,163 URTI and 105 UTI cases.
Main Results:
- Prescribing rates for URTI and UTI were 33.8% and 57.1%, respectively.
- Private clinics showed higher URTI antibiotic prescribing than public clinics.
- Penicillins and macrolides were common for URTI, with underuse of penicillin V; penicillins and cotrimoxazole dominated UTI prescriptions.
Conclusions:
- Urgent need for enhanced evidence-based antibiotic prescribing practices in Malaysian primary care.
- Particular focus required on optimizing URTI treatment in private primary care settings.
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