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Related Concept Videos

Aneurysm II: Clinical Manifestations and Diagnostic Studies01:21

Aneurysm II: Clinical Manifestations and Diagnostic Studies

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Vascular Spasm01:16

Vascular Spasm

The vascular phase, also known as vasospasm, is the initial stage of hemostasis, crucial for preventing excessive bleeding when a blood vessel is injured. After a vessel is cut, nerves in the damaged area trigger pain and other sensory impulses. Simultaneously, the smooth muscles in the vessel wall contract, resulting in a vascular spasm. This contraction reduces the vessel's diameter at the injury site, slowing or stopping blood loss through the vessel wall. Vascular spasms typically last for...
Coronary Artery Disease III: Clinical Manifestations01:30

Coronary Artery Disease III: Clinical Manifestations

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Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation

Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...
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Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations

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Related Experiment Video

Updated: Jun 1, 2026

Analysis of Cerebral Vasospasm in a Murine Model of Subarachnoid Hemorrhage with High Frequency Transcranial Duplex Ultrasound
10:41

Analysis of Cerebral Vasospasm in a Murine Model of Subarachnoid Hemorrhage with High Frequency Transcranial Duplex Ultrasound

Published on: June 3, 2021

[Symptomatic vasospasm. Clinical manifestations].

C E Scherle-Matamoros1, J Pérez-Nellar, L Fernández-Cue

  • 1Unidad de Ictus, Servicio de neurología, Hospital CQ "Hermanos Ameijeiras", Ciudad Habana, Cuba. csm@infomed.sld.cu

Neurocirugia (Asturias, Spain)
|May 21, 2011
PubMed
Summary

Symptomatic vasospasm after subarachnoid hemorrhage often presents with cognitive changes and has high mortality. Transcranial Doppler (TCD) effectively predicts cerebral ischemia from vasospasm.

Area of Science:

  • Neurology
  • Neurosurgery
  • Radiology

Context:

  • Subarachnoid hemorrhage (SAH) from ruptured saccular aneurysms can lead to symptomatic cerebral vasospasm.
  • Diagnosing vasospasm presents clinical challenges, impacting patient outcomes.
  • Cerebral vasospasm is a significant complication following aneurysmal SAH.

Purpose:

  • To describe the clinical characteristics of cerebral vasospasm.
  • To evaluate vasospasm using neurovascular studies, including Transcranial Doppler (TCD).
  • To identify predictors and clinical manifestations of symptomatic vasospasm.

Summary:

  • Cognitive and behavioral changes were the most common symptoms (53%), followed by focal deficits (26%).
  • Vasospasm predominantly affected anterior circulation arteries, occurring most frequently between days 9-10 post-SAH.

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Analysis of Cerebral Vasospasm in a Murine Model of Subarachnoid Hemorrhage with High Frequency Transcranial Duplex Ultrasound
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  • High mortality (42%) and a history of hypertension characterized patients with symptomatic vasospasm.

    • Impact:

    • Transcranial Doppler (TCD) demonstrated statistical significance in all parameters, highlighting its value in predicting cerebral ischemia.
    • Early identification of vasospasm through clinical presentation and TCD is crucial for managing SAH complications.
    • Understanding vasospasm's clinical profile aids in timely intervention and improved patient management strategies.