Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

High bone turnover in fibromyalgia.

T Appelboom1, A Schoutens

  • 1Erasmus University Hospital, University of Brussels, Belgium.

Calcified Tissue International
|May 1, 1990
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Effects of Site Preparation for Pine Forest/Switchgrass Intercropping on Water Quality.

Journal of environmental quality·2015
Same author

Which spinal lesions are associated with new bone formation in patients with ankylosing spondylitis treated with anti-TNF agents? A long-term observational study using MRI and conventional radiography.

Annals of the rheumatic diseases·2013
Same author

The European ankylosing spondylitis infliximab cohort (EASIC): a European multicentre study of long term outcomes in patients with ankylosing spondylitis treated with infliximab.

Clinical and experimental rheumatology·2011
Same author

Comparative efficacy and safety of two different molecular weight (MW) hyaluronans F60027 and Hylan G-F20 in symptomatic osteoarthritis of the knee (KOA). Results of a non inferiority, prospective, randomized, controlled trial.

Clinical and experimental rheumatology·2011
Same author

[What is new in interventional rheumatology?].

Revue medicale de Bruxelles·2008
Same author

[An Arabic anatomic board from the 13th century].

Revue medicale de Bruxelles·2006
Same journal

ODAPH (p.Arg77*) Phenotype and Onset of Ameloblast Pathology During Postsecretory Transition Demonstrated by FIB-SEM Analyses of Odaph<sup>C41*/C41*</sup> Mice.

Calcified tissue international·2026
Same journal

Cytokine Networks Reprogramming the Osteo-Immune Microenvironment in Cancer Bone Metastasis.

Calcified tissue international·2026
Same journal

Associations between controlling nutritional status and mortality in osteoporosis: evidence from NHANES, 2005-2018.

Calcified tissue international·2026
Same journal

Gut Microbiota-Derived TMAO Drives MC3T3-E1 Senescence and Osteogenic Dysfunction via cGAS-STING-NF-κB Signaling: Implications for Age-Related Bone Loss.

Calcified tissue international·2026
Same journal

Artificial Intelligence Approaches for Osteoporotic Fracture Risk Prediction Using Administrative Health Data: A Systematic Review.

Calcified tissue international·2026
Same journal

The Important Role of Polycystin in the Skeletal System.

Calcified tissue international·2026
See all related articles

Patients with fibromyalgic syndrome may have altered bone metabolism. Studies show higher pyrophosphate retention and an increased Fogelman index, suggesting accelerated bone remodeling in fibromyalgic patients.

Area of Science:

  • Rheumatology
  • Bone Metabolism
  • Skeletal Homeostasis

Background:

  • Fibromyalgia is a complex chronic pain condition.
  • Skeletal homeostasis and bone metabolism in fibromyalgia are not well understood.

Purpose of the Study:

  • To investigate potential abnormalities in skeletal homeostasis in patients with fibromyalgic syndrome.
  • To compare bone remodeling markers between fibromyalgic patients and a control group.

Main Methods:

  • Radioisotopic evaluation of skeletal remodeling.
  • Measurement of Fogelman index and 24-hour pyrophosphate retention.
  • Comparison of bone density (lumbar vertebrae, femoral neck) between groups.

Main Results:

Related Experiment Videos

  • Fibromyalgic patients (n=28) exhibited a higher Fogelman index compared to controls (n=16).
  • Increased 24-hour pyrophosphate retention was observed in the fibromyalgic group.
  • No significant differences in bone density were found between fibromyalgic patients and controls.

    • Conclusions:

    • Data suggest an accelerated bone metabolism in patients with fibromyalgic syndrome.
    • Altered skeletal remodeling may play a role in fibromyalgic syndrome, warranting further investigation.