Related Experiment Video
Updated: Jun 1, 2026

Basophil Activation Test for Allergy Diagnosis
Published on: May 31, 2021
[Hymenoptera venom allergy: new diagnostic tools and management]
D Comte1, S Petitpierre, P-A Bart
1Service d'immunologie et d'allergie CHUV, 1011 Lausanne. Denis.Comte@chuv.ch
Abstract:
Anaphylactic reactions to hymenoptera venoms are common and, in our latitudes, mainly concern wasps and bees. Recently, molecular biology techniques have contributed to identifying and to sequencing the major allergens of insect venoms and led to the production of recombinant allergens. Assays for specific IgE directed against these recombinant allergens have recently been made available in clinical practice. They provide considerable assistance in identifying the insect responsible for an anaphylactic reaction, in particular when standard tests are positive for both wasp and bee. This article focuses on these new laboratory tests and also reviews the management of patients experiencing an anaphylactic reaction after hymenoptera sting.
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