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Updated: Jun 1, 2026

Time-dependent Increase in the Network Response to the Stimulation of Neuronal Cell Cultures on Micro-electrode Arrays
Published on: May 29, 2017
Amplification of signal response at an arbitrary node of a complex network
Jie Zhou1, Yinzuo Zhou, Zonghua Liu
1Institute of Theoretical Physics and Department of Physics, East China Normal University, Shanghai, 200062, China.
Abstract:
Signal detection is generally related to network structure in both biological and engineering systems, and enormous effort has been putting into understanding the mechanism of amplification of weak signals in the aspects of self-tuning and scale-free topology. Here, we show that a third way of signal amplification exists, which does not require the scale-free topology as a necessary condition. This approach can effectively amplify the signal at an arbitrary node in a complex network by adaptively adjusting the coupling weights between the signal node and its neighbors, and thus can be used in both the local and global areas of a complex network. A theory is provided to explain its mechanism.
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