Related Experiment Video
Updated: Jun 1, 2026

03:59
Therapeutic Massage for Psychological Well-being in Geriatric Oncology
Published on: May 22, 2026
Thinking and talking about life expectancy in incurable cancer
Belinda E Kiely1, Martin R Stockler, Martin H N Tattersall
1NHMRC Clinical Trials Centre, University of Sydney, NSW, Australia.
Seminars in Oncology
|May 24, 2011
Summary
Patients with incurable cancer desire survival estimates to aid treatment decisions. Physicians struggle to provide accurate prognostic information, impacting patient care and future planning.
Area of Science:
- Oncology
- Palliative Care
- Medical Communication
Background:
- Patients with incurable cancer often seek detailed prognostic information, including survival estimates.
- Understanding life expectancy empowers patients in making informed treatment decisions and future plans.
- Physicians recognize the value of prognostic information but face challenges in providing reliable estimates and communicating them effectively.
Purpose of the Study:
- To review the implications of discussing life expectancy with patients who have incurable cancer.
- To explore the difficulties physicians encounter in estimating and communicating prognostic information.
- To address communication strategies for discussing survival scenarios with cancer patients.
Main Methods:
- Literature review on prognostic communication in oncology.
- Analysis of physician challenges in providing survival estimates.
- Discussion of patient needs for prognostic information.
Main Results:
- Patients desire specific survival scenarios (most likely, best, worst case).
- Physicians report difficulties in accurate estimation and tailored communication.
- Effective communication of prognostic information is crucial for patient decision-making.
Conclusions:
- Addressing patient needs for prognostic information is essential in incurable cancer care.
- Improving physicians' skills in estimating and communicating survival is critical.
- Open discussions about life expectancy enhance patient autonomy and planning.
Related Concept Videos
Cancer Survival Analysis
Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...
Actuarial Approach
The actuarial approach, a statistical method originally developed for life insurance risk assessment, is widely used to calculate survival rates in clinical and population studies. This method accounts for participants lost to follow-up or those who die from causes unrelated to the study, ensuring a more accurate representation of survival probabilities.
Consider the example of a high-risk surgical procedure with significant early-stage mortality. A two-year clinical study is conducted,...
Consider the example of a high-risk surgical procedure with significant early-stage mortality. A two-year clinical study is conducted,...
Cancer Stem Cells and Tumor Maintenance
Early diagnosis and treatment can often cure cancer. However, even with treatment, residual cells called cancer stem cells (CSC) might remain, often causing tumor recurrence. These cancer stem cells possess the potential for self-renewal and multi-lineage differentiation and are often responsible for the therapeutic resistance displayed in most cancers.
Cancer stem cells are thought to originate from tissue-specific normal stem cells or progenitor cells. The normal stem cells usually reside in...
Cancer stem cells are thought to originate from tissue-specific normal stem cells or progenitor cells. The normal stem cells usually reside in...
Cancer Stem Cells and Tumor Maintenance
Early diagnosis and treatment can often cure cancer. However, even with treatment, residual cells called cancer stem cells (CSC) might remain, often causing tumor recurrence. These cancer stem cells possess the potential for self-renewal and multi-lineage differentiation and are often responsible for the therapeutic resistance displayed in most cancers.
Cancer stem cells are thought to originate from tissue-specific normal stem cells or progenitor cells. The normal stem cells usually reside in...
Cancer stem cells are thought to originate from tissue-specific normal stem cells or progenitor cells. The normal stem cells usually reside in...
Cancer Therapies
Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
Cancer Therapies
Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
