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Related Experiment Video

Updated: Jun 1, 2026

Induction of Periodontitis via a Combination of Ligature and Lipopolysaccharide Injection in a Rat Model

Induction of Periodontitis via a Combination of Ligature and Lipopolysaccharide Injection in a Rat Model

Published on: February 17, 2023

[Periodontal diseases and preterm birth: a pilot study].

H Le Borgne¹, A Soueidan, Y Caroit-Cambazard

¹Service de gynécologie-obstétrique et médecine de la reproduction, hôpital Mère-Enfant, CHU de Nantes, 38, boulevard Jean-Monnet, 44093 Nantes cedex, France. helene.leborgne@chu-nantes.fr

Gynecologie, Obstetrique & Fertilite

|May 24, 2011

Summary

This summary is machine-generated.

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The establishment of the oral microbiome begins before birth, challenging the long-held belief that the fetal oral cavity is sterile. The presence of oral microbes such as Streptococcus and Fusobacterium in amniotic fluid suggests that microbial exposure may occur in utero, potentially through translocation from the maternal oral or gastrointestinal tract. This early colonization primes the neonatal immune system and sets the stage for subsequent microbial succession. Maternal health,...

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This study investigated periodontal disease prevalence in preterm births. While 33% of patients had gingivitis and 44% had periodontitis, no significant association with preterm delivery was found.

Area of Science:

Oral health
Obstetrics
Periodontology

Context:

Preterm birth poses significant risks to infant health.
Periodontal disease is a common oral condition.
The potential link between maternal oral health and pregnancy outcomes is an area of ongoing research.

Purpose:

To determine the prevalence of periodontal disease in patients experiencing preterm delivery (before 37 weeks of gestation).
To investigate if a significant association exists between periodontal diseases and preterm birth.
To correlate periodontal status and severity with the gestational age at delivery.

Summary:

Fifty-two patients were assessed for periodontal health.
Prevalence rates were 33% for gingivitis and 44% for periodontitis.

Related Experiment Videos

Last Updated: Jun 1, 2026

Induction of Periodontitis via a Combination of Ligature and Lipopolysaccharide Injection in a Rat Model

Induction of Periodontitis via a Combination of Ligature and Lipopolysaccharide Injection in a Rat Model

Published on: February 17, 2023

No statistically significant correlation (P=0.41) was found between periodontal disease and preterm delivery.

Impact:

Findings align with existing literature on periodontal disease prevalence.
Highlights the need for standardized definitions in periodontal research.
Suggests further investigation with harmonized methodologies may be required to clarify potential associations.