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Updated: Jun 1, 2026

An In vitro System to Gauge the Thrombolytic Efficacy of Histotripsy and a Lytic Drug
Published on: June 4, 2021
Advances in deep vein thrombosis management with thrombolysis
Ali Akhtar Cheema1, Robert H Mallinson, Nicola Trepte
1The Ipswich Hospital NHS Trust,Heath Road, Ipswich, Suffolk, IP4 5PD.
Abstract:
Lower extremity deep vein thrombosis (DVT) is a common disease associated with serious short term and long term complications. Its conventional treatment has been anticoagulation. Thrombolytic treatment has been used for DVT for over 40 years. More recently catheter directed thrombolysis has taken over systemic thrombolysis. This technique is useful to prevent post thrombotic syndrome (PTS) after DVT. In this review article we present a case of DVT thrombolysis in our hospital, look at the pathophysiology of PTS, the mechanism of thrombolysis and the current status of thrombolysis in DVT.
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