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Encapsulated hepatocellular carcinoma: radiologic findings and pathologic correlation
P R Ros1, B J Murphy, J L Buck
1Department of Radiologic Pathology, Armed Forces Institute of Pathology, Washington, DC.
Gastrointestinal Radiology
|January 1, 1990
Summary
Encapsulated hepatocellular carcinoma (HCC) is a slow-growing subtype with a better prognosis. This study reviews its radiographic appearance in non-Asian patients, finding similarities to Japanese cases.
Area of Science:
- Hepatobiliary pathology
- Radiology
- Oncology
Background:
- Encapsulated hepatocellular carcinoma (HCC) is a distinct pathologic subtype.
- It is characterized by slow, noninvasive growth and a favorable prognosis.
- Previously documented primarily in Japanese populations.
Purpose of the Study:
- To review the radiographic appearance of encapsulated HCC.
- To determine if this subtype occurs in non-Asian patients.
- To compare radiographic findings with existing Japanese literature.
Main Methods:
- Pathological review of 73 typical HCC cases in non-Asian patients.
- Identification of 11 cases meeting strict criteria for encapsulated HCC.
- Analysis of radiographic findings from computed tomography (CT), ultrasonography, and angiography.
Main Results:
- Encapsulated HCC was identified in 11 of 73 non-Asian patients.
- Radiographic findings included a hyperdense rim on CT (5/9 cases).
- Anechoic halo on ultrasonography (4/6 cases) and avascular rim on angiography (5/8 cases) were observed.
Conclusions:
- Encapsulated HCC occurs in non-Asian patients.
- Radiographic findings in non-Asian patients are consistent with descriptions from Japanese series.
- This subtype has similar pathological and radiological characteristics across different ethnicities.