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Updated: Jun 1, 2026

Granulocyte-dependent Autoantibody-induced Skin Blistering
Published on: October 12, 2012
Hair loss in autoimmune cutaneous bullous disorders
Maryia Miteva1, Dédée F Murrell, Antonella Tosti
1Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, 1600 North West 10th Avenue, RSMB - 2023A, Miami, FL 33136, USA.
Abstract:
The expression of the basement membrane zone (BMZ) components in the anagen hair follicles of the human scalp is similar to that of interfollicular epidermis. Expression of the BMZ components varies according to the different follicular portions. Blistering of the scalp, involving lamina lucida and below, usually leads to scarring alopecia secondary to the inflammatory process in the interfollicular epidermis and in the upper portion of the hair follicle. This article discusses the presence of alopecia in the most common acquired forms of bullous disorders.
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