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Updated: Jun 1, 2026

Granulocyte-dependent Autoantibody-induced Skin Blistering
Published on: October 12, 2012
'Picture Quiz Answers: A severe rash
1Royal Bolton Hospital NHS Trust, Bolton, BL4 0JR.
Abstract:
This patient was diagnosed as having Stevens-Johnson Syndrome. The most likely cause was the sulfasalazine, which had been started recently. This drug was stopped. He was reviewed by a dermatologist, who confirmed the diagnosis and recommended treatment with oral corticosteroids. He was commenced on prednisolone 30 mg daily and discharged 2 days after his admission. He was reviewed in the rapid access clinic the following week and his rash was resolving well and his fever had subsided. The patient was discharged back to the care of the rheumatologists.
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