Related Experiment Video

Updated: Jun 1, 2026

High Sensitivity Measurement of Transcription Factor-DNA Binding Affinities by Competitive Titration Using Fluorescence Microscopy
06:38

High Sensitivity Measurement of Transcription Factor-DNA Binding Affinities by Competitive Titration Using Fluorescence Microscopy

Published on: February 7, 2019

Photochemically amplified detection of molecular recognition events: an ultra-sensitive fluorescence turn-off binding

Tiffany P Gustafson1, Greg A Metzel, Andrei G Kutateladze

  • 1Department of Chemistry and Biochemistry, University of Denver, Denver, CO 80208, USA.

Organic & Biomolecular Chemistry
|May 25, 2011
PubMed

More Related Videos

Detection of CD40 Protein-Umbelliferone Interaction via Differential Scanning Fluorescence05:30

Detection of CD40 Protein-Umbelliferone Interaction via Differential Scanning Fluorescence

Published on: March 1, 2024

Split Hybridization Probe Utilizing a DNA Fluorescent Light-up Aptamer as a Signal Reporter for Sequence-Specific Nucleic Acid Analysis07:10

Split Hybridization Probe Utilizing a DNA Fluorescent Light-up Aptamer as a Signal Reporter for Sequence-Specific Nucleic Acid Analysis

Published on: July 8, 2025

Related Concept Videos

Labeling DNA Probes03:31

Labeling DNA Probes

DNA probes are fragments of DNA labeled with a reporter tag to enable their detection or purification. The resulting labeled DNA probes can then hybridize to target nucleic acid sequences through complementary base-pairing, and may be used to recover or identify these regions.
Radioisotopes, fluorophores, or small molecule binding partners like biotin or digoxigenin, are the most widely used reporter tags for labeling DNA probes. These labels can be attached to the probe DNA molecule via...