Cytogenetical and fish analysis on a salivary sebaceous lymphadenoma

Chromosomal studies of a cultured parotid sebaceous lymphadenoma showed two abnormal cell groups, one with trisomy 9 (15% of the metaphases) and one with inconsistent structural deviations (10%). FISH analysis showed that the trisomic clone was actually larger (36%) than that revealed by chromosomal studies. The sebaceous lymphadenoma represents the fourth type of benign salivary gland tumor to show clonal chromosomal deviations.