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Published on: December 11, 2013
[Low ankle brachial index and risk of death: a meta-analysis]
Ying Dong1, Jin-Ming Yu, Da-Yi Hu
1Clinical Research Institute and Key Laboratory of Public Health Safety, Ministry of Education, School of Public Health, Fudan University, Shanghai 200032, China.
Objective:
To evaluate the association between low ankle brachial index and risk of death.
Methods:
Related cohort studies in the past 12 years were collected. Heterogeneity was analyzed with χ(2) and I(2). Pooled hazard ratio (HR) as the effect indicator and 95% confidence interval (CI) were used to estimate the association of low ankle brachial index and risk of death by fixed effect model (inverse variance method).
Results:
A total of 8 studies were included with sum sample size of 30 029. In heterogeneity analysis, χ(2) was 5.46, I(2) was 0.0%, and P was 0.604. Meta-analysis resulted in pooled HR of 1.69 (95%CI: 1.55 - 1.84).
Conclusion:
Low ankle brachial index is associated with increased risk of death.
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