Transcutaneous regional venous oximetry: a feasibility study
Robert H Thiele1, Jason M Tucker-Schwartz, Yao Lu
1Department of Anesthesiology, Charlottesville, VA 22908-0710, USA. rht7w@virginia.edu
Anesthesia and Analgesia
|May 27, 2011
Summary
This study explored transcutaneous assessment of peripheral venous oxygen saturation (Sxvo₂) at three sites. Results showed potential for non-invasive monitoring, but further validation is needed.
Area of Science:
- Biomedical Engineering
- Anesthesiology
- Medical Monitoring
Background:
- Arterial pulse oximetry is a standard anesthesia monitor but doesn't fully assess regional oxygen delivery adequacy.
- Peripheral or regional venous oxygen saturation (Sxvo₂) offers insights into oxygen supply and demand.
- Current methods for Sxvo₂ assessment are limited.
Purpose of the Study:
- To evaluate the suitability of three anatomical sites for transcutaneous assessment of Sxvo₂.
- To explore a non-invasive method for measuring regional oxygen saturation.
- To determine the feasibility of using reflectance oximetry for Sxvo₂ estimation.
Main Methods:
- A Nonin reflectance oximetry probe was used on volunteers at the antecubital, external jugular, and internal jugular veins.
- Absorbance of red and infrared light was measured, and fast Fourier transformation was applied to waveforms.
- Sxvo₂ was calculated using empiric correlations based on absorbance ratios.
Main Results:
- Transcutaneous Sxvo₂ estimates varied widely (41%-97%), with mean values of 75%, 80%, and 80% at the antecubital, external jugular, and internal jugular veins, respectively.
- A high percentage (93%) of predicted Sxvo₂ values were below 90%.
- The study demonstrated the potential for transcutaneous Sxvo₂ measurement at these sites.
Conclusions:
- Further validation with venous blood gas measurements is essential.
- Integrating technologies like fetal reflectance oximetry and near-infrared spectroscopy could improve accuracy.
- Advanced signal processing techniques are needed for technique refinement.
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