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A novel biflavonyloxymethane from Pongamia pinnata and its radical quenching activity
Anindita Ghosh1, Suvra Mandal, Avijit Banerji
1Centre of Advanced Studies on Natural Products including Organic Synthesis, Department of Chemistry, Calcutta University, 92 A.P.C.Road, Kolkata-700 009, India.
Abstract:
The root bark of Pongamia pinnata Pierre (syn P. glabra Vent.) has afforded a new biflavonyloxymethane, pongabiflavone, along with a known furanoflavone, 3-methoxy-(7, 8, 2", 3") furanoflavone. The structure of this new compound was elucidated from extensive spectral studies, including 2D-NMR spectroscopic experiments. The antioxidant, radical quenching activity- superoxide and nitric oxide quenching activities of both pongabiflavone and previously isolated karanjabiflavone have been evaluated which can be a key to cure Psoriasis.
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