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Detection of Polyfunctional T Cells in Children Vaccinated with Japanese Encephalitis Vaccine via the Flow Cytometry Technique
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Update on Japanese encephalitis vaccine for children: United States, May 2011

    MMWR. Morbidity and Mortality Weekly Report
    |May 28, 2011
    PubMed

    Insights

    The inactivated mouse brain-derived Japanese encephalitis (JE) vaccine (JE-MB), previously the only U.S.-licensed option for children, is unavailable. This notice offers guidance on alternative JE vaccine access for U.S. pediatric populations.

    Area of Science:

    • Immunology
    • Vaccinology
    • Public Health

    Background:

    • The inactivated mouse brain-derived Japanese encephalitis (JE) vaccine (JE-MB), also known as JE-Vax, was the sole JE vaccine approved for pediatric use in the United States.
    • The discontinuation of JE-MB presents a challenge for pediatric Japanese encephalitis prevention in the U.S.

    Purpose of the Study:

    • To inform healthcare providers and the public about the unavailability of the JE-MB vaccine.
    • To provide updated information on available options for obtaining Japanese encephalitis vaccine for children in the United States.

    Main Methods:

    • This is a notice providing updated information, not a research study.
    • Information dissemination regarding vaccine availability and procurement.

    Main Results:

    • The JE-MB vaccine is no longer available for use.
    • Alternative strategies for accessing JE vaccine for U.S. children are being communicated.

    Conclusions:

    • Healthcare providers and parents need to be aware of the JE-MB vaccine's unavailability.
    • Guidance on alternative JE vaccine acquisition is crucial for maintaining pediatric immunization against Japanese encephalitis.

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