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An Adoptive Transfer Model of Rheumatoid Arthritis in Mice

Published on: June 6, 2025

Epigenetic deregulation in rheumatoid arthritis

Emmanuel Karouzakis1, Renate E Gay, Steffen Gay

  • 1Center for Experimental Rheumatology, University Hospital Zurich, Gloriastrasse, Zurich, Switzerland.

Advances in Experimental Medicine and Biology
|June 2, 2011
PubMed
Summary

Epigenetic alterations, including DNA methylation and histone modifications in the immune system and synovial fibroblasts, are implicated in rheumatoid arthritis pathogenesis. Future epigenetic therapies are being explored to target these changes.

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