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Metastatic testicular cancer and extragonadal germ cell tumor presenting with neurological symptoms
N Borge1, S D Fosså, A E Stenwig
1Department of Oncology, Norwegian Radium Hospital, Oslo.
Abstract:
We present two patients with testicular cancer and extragonadal germ cell tumor respectively in whom neurological symptoms due to metastases preceded the correct diagnosis. Testicular cancer and extragonadal germ cell tumor are today curable malignancies even when distant metastases are present at diagnosis. The diagnosis of germ cell tumor should be considered whenever a young man presents with metastases of uncertain origin, and all histological specimens should be revised with the diagnosis of germ cell tumor in mind.
Insights
Neurological symptoms can precede diagnosis in young men with testicular cancer or extragonadal germ cell tumors. Early consideration of germ cell tumors in cases of unexplained metastases is crucial for timely diagnosis and curable treatment.
Area of Science:
- Oncology
- Neurology
- Pathology
Background:
- Testicular cancer and extragonadal germ cell tumors are curable malignancies.
- Metastatic disease can present with diverse symptoms, sometimes preceding the primary tumor diagnosis.