Factors associated with blood pressure control in diabetic patients treated in nephrology units. PRESDIAB Study

N Serra1, A Oliveras, S Bergoñon

  • 1Nephrology Department, Clínic Hospital, Barcelona, Spain.

Insights

Tight blood pressure control is achieved by less than 20% of type 2 diabetes patients in nephrology units. High LDL cholesterol levels are significantly associated with uncontrolled hypertension in this population.

Area of Science:

  • Nephrology
  • Cardiology
  • Endocrinology

Background:

  • Hypertension management in diabetic patients remains a significant clinical challenge.
  • Type 2 diabetes (DM2) patients often exhibit suboptimal blood pressure (BP) control.
  • Nephrology units manage a high-risk population with co-existing DM2 and arterial hypertension (AHT).

Purpose of the Study:

  • To determine the prevalence of tight BP control (<130/80mm Hg) in DM2 patients treated in nephrology units.
  • To identify factors associated with achieving or failing to achieve target BP in this cohort.
  • To inform clinical strategies for improving BP management in diabetic hypertensive patients.

Main Methods:

  • An observational, cross-sectional study design was employed.
  • 526 patients with DM2 and AHT were included in the analysis.
  • Data collected included demographics, clinical characteristics, BP, kidney function, glycemic control, lipid profile, and medications.

Main Results:

  • Only 17.5% of patients achieved tight BP control (<130/80mm Hg).
  • Elevated LDL cholesterol levels were significantly associated with uncontrolled BP (OR 0.55; 95% CI:0.41-0.75).
  • A majority of patients (71%) were on two or more antihypertensive medications.

Conclusions:

  • Less than 20% of DM2 patients in nephrology units achieve target BP control.
  • Elevated cholesterol levels are a key factor linked to poor BP control in this population.
  • Improved management of dyslipidemia may be crucial for optimizing BP control in diabetic hypertensive patients.
Abstract

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