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Mucormycosis infection following intravenous access in the forearm
Ronit Wollstein1, Alka Palekar
1Department of Surgery, Division of Plastic and Reconstructive Surgery;
Abstract:
Mucormycosis is an opportunistic infection that is often fatal, requiring aggressive local control as well as systemic therapy. A rare case of a forearm infection originating in a traumatic intravenous access portal is described in the present study. The Mucor species infection prevented liver transplant, and the patient passed away. In the present case, it was decided to limit the resection to the skin and subcutaneous tissue based on a frozen section and the viability of the biopsied tissue. With consistently rising numbers of immunocompromised patients, awareness and familiarity with mucormycosis in the extremities is important. Knowing that a minimal traumatic event may precede the infection could assist in prevention and early diagnosis. Guidelines for pathological and clinical diagnosis and treatment need to be further clarified.
Insights
Mucormycosis, a fatal fungal infection, can occur in extremities from minor trauma. Early diagnosis and treatment are crucial, especially in immunocompromised patients, though guidelines need improvement.
Area of Science:
- Mycology
- Infectious Diseases
- Clinical Case Study
Background:
- Mucormycosis is a severe opportunistic infection demanding prompt intervention.
- Extremity infections are rare but carry a high mortality rate.
- Immunocompromised populations are increasingly susceptible.
Observation:
- A rare case of forearm mucormycosis is presented, originating from an intravenous access site.
- The infection complicated a planned liver transplant, leading to patient demise.
- Surgical management involved limited resection based on intraoperative frozen section analysis.
Findings:
- Mucor species infection was confirmed.
- The infection's severity precluded liver transplantation.
- Tissue viability assessment guided conservative surgical approach.
Implications:
- Highlights the importance of recognizing extremity mucormycosis in immunocompromised individuals.
- Suggests minor trauma can be a precursor, aiding early detection.
- Underscores the need for refined diagnostic and therapeutic guidelines for this condition.
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