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Function of the A-type cyclins during gametogenesis and early embryogenesis

Debra J Wolgemuth1

  • 1Department of Genetics and Development, Columbia University Medical Center, Russ Berrie 608, 1150 St. Nicholas Avenue, New York, NY 10032, USA. djw3@columbia.edu

Results and Problems in Cell Differentiation
|June 2, 2011
PubMed
Summary

A-type cyclins regulate cell cycle progression. Cyclin A1 loss causes male sterility by disrupting meiosis, while cyclin A2 deficiency leads to embryonic lethality in mice, highlighting their distinct roles.

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