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Diagnostic studies
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Pharmacogenomics: Identification of New Drug Targets

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Chronic Pancreatitis II: Pathophysiology01:21

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Related Experiment Video

Updated: Jun 1, 2026

Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis
10:27

Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis

Published on: December 15, 2011

Recent advances in celiac disease.

Hugh James Freeman, Angeli Chopra, Michael Tom Clandinin

    World Journal of Gastroenterology
    |June 3, 2011
    PubMed
    Summary
    This summary is machine-generated.

    Celiac disease affects 1 in 100 individuals in Europe and North America. Recent advancements include understanding genetic predispositions like HLA-DQ2/DQ8, potential celiac disease, and new diagnostic techniques.

    Keywords:
    InfectionInflammationMalabsorptionPathophysiologyPhysiology

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    Last Updated: Jun 1, 2026

    Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis
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    Published on: December 15, 2011

    A High-Throughput Multiplexed Screening for Type 1 Diabetes, Celiac Diseases, and COVID-19
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    A High-Throughput Multiplexed Screening for Type 1 Diabetes, Celiac Diseases, and COVID-19

    Published on: July 5, 2022

    Area of Science:

    • Gastroenterology and Immunology
    • Clinical Medicine

    Background:

    • Celiac disease prevalence is significant, affecting approximately 1% of populations in Europe and North America.
    • Understanding the genetic basis, particularly HLA-DQ2 and HLA-DQ8, is crucial for predisposition.
    • The spectrum of celiac disease now includes the concept of potential celiac disease.

    Discussion:

    • Recent developments focus on clinical associations and diagnostic advancements.
    • New imaging and endoscopy techniques are improving detection and management.
    • The emergence of refractory celiac disease presents ongoing clinical challenges.

    Key Insights:

    • Genetic factors (HLA-DQ2/DQ8) play a key role in celiac disease susceptibility.
    • The diagnostic landscape is evolving with novel imaging and endoscopic approaches.
    • Refractory celiac disease requires specialized management strategies.

    Outlook:

    • Continued research into clinical associations and genetic predispositions is expected.
    • Further refinement of imaging and endoscopy will enhance diagnostic accuracy.
    • Developing effective treatments for refractory celiac disease remains a priority.