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Updated: Jun 1, 2026

Separation of Immune Cell Subpopulations in Peripheral Blood Samples from Children with Infectious Mononucleosis
Published on: September 7, 2022
Multiple calcified primary central nervous system lymphoma with immunodeficiency in a child
Jing-Qi Zhu1, Nan-Xin Hao, Wei-Qun Bao
1Department of Radiology, East Hospital, Tongji University School of Medicine, Shanghai, 200120, China.
Background:
Multiple calcified primary central nervous system lymphoma (PCNSL) is extremely rare in childhood.
Methods:
We report a 4-year-old boy suffering from multiple calcified B-cell lymphoma in the brain with immunodeficiency.
Results:
The boy had a history of walking weakness and seizure for 4 months. The serum levels of immunoglobulin G, A and M were decreased. Brain MRI showed multiple lesions which had ring enhancement. CT showed calcification in all of the lesions. The boy was firstly misdiagnosed with multiple chronic brain abscesses. Pathological analysis of biopsy confirmed the diagnosis of anaplastic diffuse large B-cell lymphoma.
Conclusion:
PCNSL should be included in the differential diagnosis of intracranial mass with calcification.
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