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Related Concept Videos

Liver Regeneration01:24

Liver Regeneration

The liver is an important organ in vertebrates that plays an essential role in metabolism. It is also responsible for storing and redistributing nutrients such as carbohydrates, fats, and vitamins in the body. Additionally, the liver releases bile salts which are critical for digesting food and eliminating toxic metabolites from the body.
Cells of Liver
The liver comprises four major types of cells— hepatocytes, stellate, Kupffer, and sinusoidal endothelial cells. The hepatocytes are large...
Effect of Hepatic Disease on Pharmacokinetics: Pathophysiologic Assessment and Liver Function Test01:22

Effect of Hepatic Disease on Pharmacokinetics: Pathophysiologic Assessment and Liver Function Test

In clinical practice, the direct measurement of hepatic blood flow to evaluate liver function presents significant challenges due to the intricate and specialized nature of the necessary techniques. Consequently, healthcare professionals often rely on empirical estimates derived from thorough patient examinations and liver function tests to gauge liver health. Among the tools at their disposal, the Child–Pugh and MELD scoring systems stand out for their ability to categorize and assess the...

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Related Experiment Video

Updated: Jun 1, 2026

Rat Model of the Associating Liver Partition and Portal Vein Ligation for Staged Hepatectomy (ALPPS) Procedure
07:29

Rat Model of the Associating Liver Partition and Portal Vein Ligation for Staged Hepatectomy (ALPPS) Procedure

Published on: August 14, 2017

Liver allocation and distribution: possible next steps.

Kenneth Washburn1, Elizabeth Pomfret, John Roberts

  • 1Transplant Center, University of Texas Health Science Center, San Antonio, TX 78229, USA. washburn@uthscsa.edu

Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society
|June 3, 2011
PubMed
Summary
This summary is machine-generated.

Improving cadaveric liver allograft distribution is crucial for reducing wait-list mortality. A comprehensive 2-year deliberative process informed potential recommendations for liver transplantation.

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Porcine Liver Transplantation Without Veno-Venous Bypass As an Extended Criteria Donor Model
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Porcine Liver Transplantation Without Veno-Venous Bypass As an Extended Criteria Donor Model

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Related Experiment Videos

Last Updated: Jun 1, 2026

Rat Model of the Associating Liver Partition and Portal Vein Ligation for Staged Hepatectomy (ALPPS) Procedure
07:29

Rat Model of the Associating Liver Partition and Portal Vein Ligation for Staged Hepatectomy (ALPPS) Procedure

Published on: August 14, 2017

Porcine Liver Transplantation Without Veno-Venous Bypass As an Extended Criteria Donor Model
12:49

Porcine Liver Transplantation Without Veno-Venous Bypass As an Extended Criteria Donor Model

Published on: August 17, 2022

Area of Science:

  • Organ transplantation
  • Medical policy

Background:

  • Discussions regarding cadaveric liver allograft distribution highlight critical issues.
  • Wait-list mortality remains a significant concern in liver transplantation.

Purpose of the Study:

  • To describe the deliberative process undertaken over two years.
  • To interpret feedback and responses regarding liver allograft distribution.
  • To propose possible recommendations for improving the process.

Main Methods:

  • A multi-faceted approach including discussions and public forums.
  • Data modeling and a request for public information.
  • Development of a concept document based on feedback.

Main Results:

  • A focused path towards reducing wait-list mortality has emerged.
  • Significant public and expert engagement was documented.
  • Key issues in allograft distribution have been identified.

Conclusions:

  • The deliberative process has clarified potential strategies for improving liver allograft distribution.
  • Recommendations are being formulated to address identified challenges.
  • The study emphasizes a structured approach to policy development in transplantation.