Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Mechanical Ventilation II: Invasive Ventilation

Mechanical Ventilation II: Invasive Ventilation

Ventilators are essential medical equipment used to aid patients with respiratory difficulties. Their primary function is to assist or replace spontaneous breathing by providing mechanical ventilation. There are two general classes of mechanical ventilators: negative-pressure and positive-pressure ventilators.
Negative-Pressure Ventilators
Negative-pressure ventilators create a vacuum around the chest or body to draw air into the lungs, simulating breathing. This method does not require an...

Mechanical Ventilation III: Noninvasive Ventilation

Mechanical Ventilation III: Noninvasive Ventilation

Noninvasive positive-pressure ventilation (NIPPV), continuous positive airway pressure (CPAP), and bilevel positive airway pressure (BiPAP) are essential methods in respiratory care. These ventilation techniques offer unique benefits for patients with various respiratory conditions, providing adequate support without requiring intubation. Let's explore how each method is crucial in improving patient outcomes and enhancing respiratory therapy.
Noninvasive Positive-Pressure Ventilation (NIPPV)

Ventilatory Modes

Ventilatory Modes

Mechanical ventilators are life-saving devices that support or replace spontaneous breathing. They deliver breaths to patients through varying methods known as ventilator modes. Understanding these modes is critical for healthcare providers managing patients with respiratory failure.
There are three ventilatory modes: full support, partial support, and spontaneous. These are described below.
Full Support Modes
Full support modes include controlled mechanical ventilation, continuous mandatory...

Mechanical Ventilation I: Indication and Settings

Mechanical Ventilation I: Indication and Settings

Mechanical ventilation is a life-saving technique for managing acute respiratory failure and other respiratory complications. The process involves using a machine known as a ventilator to supply oxygen to the lungs and assist in removing carbon dioxide. It serves as a bridge to long-term mechanical ventilation or a temporary measure until ventilatory support is discontinued. The ventilator can maintain this function for a prolonged period, providing critical support for patients until they can...

Assessment of Ventilation I: Respiratory Rate

Assessment of Ventilation I: Respiratory Rate

Assessment of Ventilation
A Ventilation assessment is critical for monitoring a patient's health status. Respiration, one of the most accessible vital signs, provides insights into the function of numerous body systems and can indicate serious health issues, such as brainstem injuries from head trauma.
Critical Guidelines for Assessing Ventilation:

Cardiopulmonary Resuscitation II: ACLS Airway Management

Cardiopulmonary Resuscitation II: ACLS Airway Management

Airway management is a key skill in emergency and critical care settings, as maintaining a clear airway is essential for adequate oxygenation and ventilation.Head Tilt-Chin Lift TechniqueThe head tilt-chin lift maneuver is an essential technique primarily used in patients without suspected cervical spine injuries. To perform this maneuver, one hand is placed on the patient’s forehead, and gentle pressure is applied backward to tilt the head. The fingertips of the other hand are positioned under...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Neonatal Outcomes Following Antenatal Identification of Twin-To-Twin Transfusion Syndrome.

Acta paediatrica (Oslo, Norway : 1992)·2026

Same author

Role of the Chest Wall in Newborn Respiratory Function at Birth.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology·2025

Same author

3DMPR - a robust morphological approach for applying phase retrieval in proximity to highly attenuating objects in computed tomography.

Journal of synchrotron radiation·2025

Same author

Non-invasive ventilation of preterm infants in the delivery room.

Seminars in perinatology·2025

Same author

External negative pressure improves lung aeration in near-term rabbit kittens at risk of developing respiratory distress.

Frontiers in pediatrics·2025

Same author

Comparison of "IN-REC-SUR-E" and LISA in preterm neonates with respiratory distress syndrome: a randomized controlled trial (IN-REC-LISA trial).

Trials·2024

Search research articles

Related Experiment Video

Updated: Jun 1, 2026

Mechanical Ventilation Boot Camp Curriculum

Mechanical Ventilation Boot Camp Curriculum

Published on: March 12, 2018

Lower back-up rates improve ventilator triggering during assist-control ventilation: a randomized crossover trial.

K I Wheeler¹, C J Morley, S B Hooper

¹Newborn Research, The Royal Women's Hospital, Melbourne, Victoria, Australia. kevin.wheeler@thewomens.org.au

Journal of Perinatology : Official Journal of the California Perinatal Association

|June 4, 2011

Summary

Lowering back-up ventilation rates (BURs) in assist-control/volume guarantee ventilation (AC/VG) increases triggered inflations in preterm infants. Patient cardiorespiratory stability remained unaffected across different BUR settings.

Related Experiment Videos

Last Updated: Jun 1, 2026

Mechanical Ventilation Boot Camp Curriculum

Mechanical Ventilation Boot Camp Curriculum

Published on: March 12, 2018

Area of Science:

Neonatal critical care
Respiratory physiology
Mechanical ventilation

Background:

Assist-control/volume guarantee ventilation (AC/VG) is common in preterm infants.
Back-up ventilation rates (BURs) influence ventilator-patient synchrony.
Optimizing BURs is crucial for effective respiratory support.

Purpose of the Study:

To compare the impact of different BURs (30, 40, 50 min⁻¹) on triggered inflations.
To assess patient cardiorespiratory stability under varying BURs during AC/VG ventilation.

Main Methods:

Randomized crossover trial in a tertiary Australian NICU.
26 stable preterm infants on AC/VG ventilation were studied.
Ventilator and cardiorespiratory parameters were recorded at different BUR settings.

Main Results:

Higher triggered inflation proportions observed at lower BURs (85% at 30 min⁻¹ vs. 61% at 50 min⁻¹).
Total delivered inflation rates increased slightly with higher BURs.
No significant variations in cardiorespiratory parameters, including CO2 levels, were found across settings.

Conclusions:

Lowering BURs enhances ventilator-patient triggering during AC/VG.
Cardiorespiratory stability is maintained across a range of BURs in stable preterm infants.