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Related Concept Videos

Protein Organization01:24

Protein Organization

Proteins are polymers of amino acid residues. They are versatile and responsible for different cellular functions, including DNA replication, molecular transport, catalysis, and structural support. Proteins have a hierarchical structure comprising at least three levels of organization: primary, secondary, and tertiary structure. Some large proteins have a quaternary structure where individual protein subunits are linked together.
The primary structure of a protein is its amino acid sequence.
Protein Organization01:13

Protein Organization

Overview
Protein Organization01:13

Protein Organization

Overview
Protein Organization01:24

Protein Organization

Proteins are polymers of amino acid residues. They are versatile and responsible for different cellular functions, including DNA replication, molecular transport, catalysis, and structural support. Proteins have a hierarchical structure comprising at least three levels of organization: primary, secondary, and tertiary structure. Some large proteins have a quaternary structure where individual protein subunits are linked together.
The primary structure of a protein is its amino acid sequence.
Protein and Protein Structures02:15

Protein and Protein Structures

Proteins are one of the most abundant organic molecules in living systems and have the most diverse range of functions of all macromolecules. Proteins may be structural, regulatory, contractile, or protective. They may serve in transport, storage, or membranes; or they may be toxins or enzymes. Their structures, like their functions, vary greatly. They are all, however, amino acid polymers arranged in a linear sequence.
A protein's shape is critical to its function. For example, an enzyme can...
Protein Folding01:22

Protein Folding

Overview

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3D Printing of Biomolecular Models for Research and Pedagogy
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Tactile teaching: Exploring protein structure/function using physical models*.

Tim Herman1, Jennifer Morris, Shannon Colton

  • 1MSOE Center for BioMolecular Modeling, Milwaukee School of Engineering, Milwaukee, Wisconsin 53213. herman@msoe.edu.

Biochemistry and Molecular Biology Education : a Bimonthly Publication of the International Union of Biochemistry and Molecular Biology
|June 4, 2011
PubMed
Summary
This summary is machine-generated.

Physical protein models enhance teaching of complex biological concepts. This approach benefits high school teachers, students, and undergraduate education, improving understanding of protein structure and function.

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Last Updated: Jun 1, 2026

3D Printing of Biomolecular Models for Research and Pedagogy
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Area of Science:

  • Biochemistry
  • Structural Biology
  • Science Education

Background:

  • Physical models can be constructed from solved protein atomic coordinates.
  • Effective teaching of protein structure and function remains a challenge.
  • Current educational methods may not fully convey complex protein dynamics.

Purpose of the Study:

  • To review experiences using physical protein models in high school and undergraduate education.
  • To explore the utility of physical models in teaching difficult protein structure-function concepts.
  • To demonstrate the application of physical models in specific biological examples.

Main Methods:

  • Utilizing physical models in professional development for high school biology and chemistry teachers.
  • Implementing hands-on physical protein modeling activities in student enrichment programs.
  • Applying physical models to illustrate concepts like enzyme active site packing and protein conformational changes.

Main Results:

  • Physical models are effective tools for professional development and student enrichment in high school.
  • Models aid in communicating complex undergraduate-level concepts, such as enzyme active site structure.
  • Physical models successfully illustrate dynamic processes like pH-induced protein conformational changes.

Conclusions:

  • Physical protein models offer a valuable, tangible approach to teaching complex biological structures and functions.
  • The use of physical models can significantly improve student and teacher comprehension across educational levels.
  • Physical modeling represents a promising pedagogical strategy for advancing biological education.