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Related Concept Videos

Assessment of Diffusion and Perfusion01:17

Assessment of Diffusion and Perfusion

Understanding and evaluating diffusion and perfusion is critical in assessing a patient's respiratory and circulatory health. These processes play key roles in maintaining the body's internal environment, ensuring that tissues receive adequate oxygen while waste products are efficiently removed.
The Role of Diffusion in Respiration
Diffusion is the process by which molecules move from an area of higher concentration to an area of lower concentration. In the respiratory system, this principle...

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Updated: Jun 1, 2026

Simultaneous PET/MRI Imaging During Mouse Cerebral Hypoxia-ischemia
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Published on: September 20, 2015

CT perfusion imaging in acute stroke.

Angelos A Konstas1, Max Wintermark, Michael H Lev

  • 1Department of Radiology, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114, USA. akonstas@partners.org

Neuroimaging Clinics of North America
|June 7, 2011
PubMed
Summary
This summary is machine-generated.

Computed tomographic perfusion (CTP) imaging offers crucial insights into brain hemodynamics for acute stroke patients. This review covers CTP

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Last Updated: Jun 1, 2026

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Integrated Photoacoustic, Ultrasound, and Angiographic Tomography (PAUSAT) for NonInvasive Whole-Brain Imaging of Ischemic Stroke
06:45

Integrated Photoacoustic, Ultrasound, and Angiographic Tomography (PAUSAT) for NonInvasive Whole-Brain Imaging of Ischemic Stroke

Published on: June 2, 2023

Area of Science:

  • Neuroimaging
  • Radiology
  • Cerebrovascular Disease

Background:

  • Computed tomographic perfusion (CTP) imaging provides detailed hemodynamic information at the capillary level in the brain parenchyma.
  • CTP is vital for diagnosing, managing, and predicting outcomes in acute stroke patients.
  • It helps differentiate between salvageable brain tissue, infarcted core tissue, and benign oligemia.

Purpose of the Study:

  • To review the role of CTP in acute stroke assessment.
  • To discuss the clinical applications of CTP in clarifying cerebral physiology and hemodynamic status.
  • To address concerns regarding radiation dose in CTP imaging.

Main Methods:

  • Review of existing literature and clinical applications of CTP in stroke.
  • Analysis of CTP's ability to distinguish different tissue states (salvageable, core infarct, benign oligemia).
  • Discussion of qualitative assessment of ischemia for clinical guidance.

Main Results:

  • CTP provides essential data on brain hemodynamics for acute stroke management.
  • It aids in distinguishing critically hypoperfused tissue from irreversibly infarcted tissue and metabolically stable tissue.
  • Qualitative ischemia assessment using CTP is crucial for guiding treatment decisions.

Conclusions:

  • CTP imaging is a valuable tool in the acute stroke pathway.
  • Understanding hemodynamic status via CTP improves patient management and prognosis.
  • Ongoing concerns about radiation dose require consideration and further research.