[Diastolic retrograde arterial flow: preliminary report]
M J Mc Loughlin1, S Mc Loughlin, J Milei
1Instituto de Investigaciones Cardiológicas Alberto C. Taquini (ININCA) UBA-CONICET, Buenos Aires, Argentina. santimcl@gmail.com
Radiologia
|June 7, 2011
Summary
Holodiastolic reflux, a blood flow pattern typically seen in disease, was observed in the brachial artery of healthy individuals when their arms were raised. This physiological phenomenon in normal patients warrants further study.
Area of Science:
- Vascular Ultrasound
- Hemodynamics
- Physiology
Context:
- Holodiastolic arterial blood flow is generally considered pathological.
- Previous observations suggest this flow pattern may occur in healthy individuals under specific conditions.
- The brachial artery is a key vessel for assessing upper extremity circulation.
Purpose:
- To investigate the frequency and characteristics of holodiastolic arterial blood flow in the brachial artery of healthy subjects.
- To determine if arm elevation influences brachial artery blood flow patterns.
- To differentiate physiological holodiastolic flow from pathological conditions.
Summary:
- Ten healthy volunteers underwent ultrasound assessment of the brachial artery.
- Measurements were taken in supine position, with the arm raised above horizontal, and after returning to supine.
- Mid- and end-diastolic retrograde flow (holodiastolic reflux) was observed in 8/10 participants when their arms were raised, but not in baseline or post-raising measurements.
Impact:
- Demonstrates that holodiastolic reflux can be a normal physiological response in healthy individuals.
- Suggests that arm position significantly impacts brachial artery hemodynamics.
- Provides a basis for further research into the clinical significance of this finding in various pathological states.

