Chronopotentiometric studies of phosphatidylcholine bilayers modified by ergosterol
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Updated: Jun 1, 2026

Fluorescence-Based Measurements of Phosphatidylserine/Phosphatidylinositol 4-Phosphate Exchange Between Membranes
Published on: March 14, 2021
Monika Naumowicz1, Aneta Dorota Petelska, Zbigniew Artur Figaszewski
1Institute of Chemistry, University of Bialystok, Al. J. Pilsudskiego 11/4, 15-443 Bialystok, Poland. monikan@uwb.edu.pl
Abstract:
We have monitored the effect of ergosterol on electrical capacitance and electrical resistance of the phosphatidylcholine bilayer membranes using chronopotentiometry method. The chronopotentiometric characteristic of the bilayers depends on constant-current flow through the membranes. For low current values, no electroporation takes place and the membrane voltage rises exponentially to a constant value described by the Ohm's law. Based on these kinds of chronopotentiometric curves, a method of the membrane capacitance and the membrane resistance calculations is presented.
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