Related Experiment Video
Updated: Jun 1, 2026

Robot-Assisted Laparoscopic Splenectomy In Children: A Case Report with Literature Review
Published on: March 27, 2026
Cholelithiasis in a toddler with sickle cell disease
Dana Aronson Schinasi1, Rakesh D Mistry, Rakesh Mistry
1Division of Emergency Medicine, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA. aronsond@email.chop.edu
Gallstones are uncommon in young children, even those with sickle cell anemia. This case highlights symptomatic gallstones in a toddler with sickle cell disease presenting with abdominal pain.
Area of Science:
- Pediatric Gastroenterology
- Hematology
Background:
- Cholelithiasis (gallstones) is rare in pediatric populations, particularly in toddlers and school-aged children.
- Sickle cell disease (SCD) is a known risk factor for cholelithiasis, though it is still uncommon in young SCD patients.
Observation:
- A toddler with sickle cell disease presented with acute abdominal pain.
- Common causes of abdominal pain in young children with sickle cell disease include vaso-occlusive pain crisis and splenic sequestration.
Findings:
- The toddler was diagnosed with symptomatic cholelithiasis.
- This case underscores that gallstones should be considered in the differential diagnosis of abdominal pain in young children with sickle cell disease.
Implications:
- Early recognition of cholelithiasis in children with sickle cell disease is crucial for timely management.
- This case expands the differential diagnosis of abdominal pain in pediatric sickle cell disease patients.
Related Concept Videos
Cholecystitis
Urinary Tract Calculi IV: Nutrition Therapy and Prevention
Urinary Tract Calculi VI: Surgical Management
Urinary Tract Calculi V: Nursing Management
Urinary Tract Calculi II: Pathophysiology and Clinical Manifestations
Cholera
