Delayed allergic reaction after coronary angiography.

Area of Science:

• Radiology
• Vascular Imaging
• Diagnostic Procedures

Background:

• Contrast media (CM) are crucial for diagnosing vascular diseases via angiography.
• Adverse reactions to CM, categorized as chemotoxic or allergic/pseudoallergic, are a known complication.
• Late-onset reactions to CM are less common and often underreported.

Observation:

• A case of delayed adverse reaction to nonionic CM during elective coronary angiography is presented.
• The patient experienced a delayed response, which can be easily overlooked.
• This highlights the importance of recognizing less common reaction patterns.

Findings:

• Adverse reactions to CM vary in onset, presentation, severity, and management.
• Late adverse reactions require specific diagnostic and management strategies.
• Understanding the spectrum of CM reactions is vital for patient safety.

Implications:

• Clinicians should consider delayed adverse reactions in patients undergoing contrast-enhanced angiography.
• Improved recognition and reporting of late CM reactions are needed.
• This case and literature review offer recommendations for managing delayed reactions.