Ferritin and iron levels in children with autistic disorder

Sabri Hergüner1, Fatih Mehmet Keleşoğlu, Cansaran Tanıdır

  • 1Department of Child and Adolescent Psychiatry, Selcuk University, Konya, Turkey. cocukergen@yahoo.com

Insights

Iron deficiency and anemia are common in children with autism. This study found 24.1% of children with autistic disorder had iron deficiency and 15.5% had anemia, highlighting the need for iron status assessment.

Area of Science:

  • Pediatric Neurology
  • Nutritional Science
  • Developmental Pediatrics

Background:

  • Iron is crucial for cognitive, behavioral, and motor development in children.
  • Autism Spectrum Disorder (ASD) is associated with a high prevalence of iron deficiency.
  • Understanding iron status in children with ASD is essential for addressing developmental concerns.

Purpose of the Study:

  • To investigate the iron status in a cohort of children diagnosed with autistic disorder.
  • To determine the prevalence of iron deficiency and anemia in this population.

Main Methods:

  • The study included 116 children aged 3–16 years with a diagnosis of autistic disorder (DSM-IV criteria).
  • Evaluated serum ferritin, iron, hemoglobin, hematocrit, mean corpuscular volume, and red cell distribution width.
  • Statistical analysis was performed to identify correlations between iron status and age.

Main Results:

  • A significant prevalence of iron deficiency (24.1%) and anemia (15.5%) was observed in children with autistic disorder.
  • A positive correlation was found between age and ferritin levels, as well as other hematological measures.
  • These results confirm the high occurrence of iron deficiency and anemia in this group.

Conclusions:

  • Iron deficiency and anemia are common in children with autistic disorder.
  • Routine measurement of ferritin levels is recommended for individuals with autism.
  • Early detection and intervention for iron deficiency may support developmental outcomes in children with ASD.
Abstract

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