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Ferritin and iron levels in children with autistic disorder
Sabri Hergüner1, Fatih Mehmet Keleşoğlu, Cansaran Tanıdır
1Department of Child and Adolescent Psychiatry, Selcuk University, Konya, Turkey. cocukergen@yahoo.com
Insights
Iron deficiency and anemia are common in children with autism. This study found 24.1% of children with autistic disorder had iron deficiency and 15.5% had anemia, highlighting the need for iron status assessment.
Area of Science:
- Pediatric Neurology
- Nutritional Science
- Developmental Pediatrics
Background:
- Iron is crucial for cognitive, behavioral, and motor development in children.
- Autism Spectrum Disorder (ASD) is associated with a high prevalence of iron deficiency.
- Understanding iron status in children with ASD is essential for addressing developmental concerns.
Purpose of the Study:
- To investigate the iron status in a cohort of children diagnosed with autistic disorder.
- To determine the prevalence of iron deficiency and anemia in this population.
Main Methods:
- The study included 116 children aged 3–16 years with a diagnosis of autistic disorder (DSM-IV criteria).
- Evaluated serum ferritin, iron, hemoglobin, hematocrit, mean corpuscular volume, and red cell distribution width.
- Statistical analysis was performed to identify correlations between iron status and age.
Main Results:
- A significant prevalence of iron deficiency (24.1%) and anemia (15.5%) was observed in children with autistic disorder.
- A positive correlation was found between age and ferritin levels, as well as other hematological measures.
- These results confirm the high occurrence of iron deficiency and anemia in this group.
Conclusions:
- Iron deficiency and anemia are common in children with autistic disorder.
- Routine measurement of ferritin levels is recommended for individuals with autism.
- Early detection and intervention for iron deficiency may support developmental outcomes in children with ASD.
Unlabelled:
Iron has an important role on cognitive, behavioral, and motor development. High prevalence of iron deficiency has been reported in autism. The aim of this study was to investigate iron status in a group of children with autistic disorder. The sample was composed of 116 children between 3 and 16 years with a diagnosis of autistic disorder according to DSM-IV criteria. Serum ferritin, iron, hemoglobin, hematocrit, mean corpuscular volume, and red cell distribution width values were measured. We found that 24.1% of subjects had iron deficiency, and 15.5% had anemia. There was a significant positive correlation between age and ferritin and hematological measures. Results of this study confirmed that iron deficiency and anemia are common in children with autistic disorder.
Conclusion:
These findings suggest that ferritin levels should be measured in subjects with autism as a part of routine investigation.
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Autism Spectrum Disorder
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