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Nonhealing scalp wound infected with Aspergillus niger in an elderly patient
Amanda Robinson1, Sari Fien, Marcelle A Grassi
1Department of Dermatology, University at Buffalo School of Medicine and Biomedical Sciences, New York, NY, USA. robinsonama@gmail.com
Abstract:
Cutaneous aspergillosis is a rare infection most often seen in immunocompromised patients. We report a case of primary cutaneous aspergillosis infection in a nonhealing scalp wound of an immunocompetent elderly patient. The patient had a cutaneous malignancy of the scalp treated with surgical excision but complicated by poor wound healing. Fungal culture of the nonhealing wound revealed Aspergillus niger. The nonhealing wound subsequently resolved with retapamulin ointment 1% and ketoconazole gel 2%.
Insights
A rare fungal skin infection, cutaneous aspergillosis, occurred in an immunocompetent patient. Treatment with retapamulin and ketoconazole successfully healed a nonhealing scalp wound.
Area of Science:
- Dermatology
- Mycology
- Infectious Diseases
Background:
- Cutaneous aspergillosis is typically observed in immunocompromised individuals.
- It presents as a rare skin infection.
- This case highlights an unusual presentation in an immunocompetent host.
Observation:
- An elderly, immunocompetent patient developed a nonhealing scalp wound after surgery for cutaneous malignancy.
- Fungal culture identified Aspergillus niger as the causative agent.
- The wound failed to heal despite standard care.
Findings:
- Primary cutaneous aspergillosis was diagnosed in an immunocompetent elderly patient.
- Aspergillus niger was successfully eradicated from the nonhealing scalp wound.
- Combined topical therapy with retapamulin ointment and ketoconazole gel achieved complete wound resolution.
Implications:
- This case expands the understanding of cutaneous aspergillosis presentation and risk factors.
- It suggests that immunocompetent individuals can develop this infection, particularly with compromised skin barriers.
- The successful treatment highlights the efficacy of topical antifungal and antimicrobial agents in managing such rare infections.
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