Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

DNA Microarrays02:34

DNA Microarrays

Microarrays are high-throughput and relatively inexpensive assays that can be automated to analyze large quantities of data at a time. They are used in genome-wide studies to compare gene or protein expression under two varied conditions, such as healthy and diseased states. Microarrays consist of glass or silica slides on which probe molecules are covalently attached through surface functionalization. Most commonly, the slides are prepared through the chemisorption of silanes to silica...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

First Report of Soilborne Wheat Mosaic Virus in the United Kingdom.

Plant disease·2019
Same author

Necroptosis suppresses inflammation via termination of TNF- or LPS-induced cytokine and chemokine production.

Cell death and differentiation·2015
Same author

Product Review: Near-IR gets the job done.

Analytical chemistry·2011
Same author

Product Review: GC/MS: Not the same old combination.

Analytical chemistry·2011
Same author

Product Review: Electrospray in flight.

Analytical chemistry·2011
Same author

Focus: The incredible shrinking mass spectrometers.

Analytical chemistry·2011

Related Experiment Video

Updated: Jun 1, 2026

Bacterial Gene Expression Analysis Using Microarrays
29:41

Bacterial Gene Expression Analysis Using Microarrays

Published on: May 28, 2007

Focus: DNA microarrays in toxicology.

C M Henry

    Analytical Chemistry
    |June 9, 2011
    PubMed
    Summary
    This summary is machine-generated.

    Gene expression analysis is revolutionizing toxicology by providing deeper insights into how chemicals affect biological systems. This approach offers a more precise understanding of toxicological mechanisms and potential health risks.

    More Related Videos

    DNA Microarrays: Sample Quality Control, Array Hybridization and Scanning
    09:27

    DNA Microarrays: Sample Quality Control, Array Hybridization and Scanning

    Published on: March 15, 2011

    Experimental Protocol for Detecting Cyanobacteria in Liquid and Solid Samples with an Antibody Microarray Chip
    10:57

    Experimental Protocol for Detecting Cyanobacteria in Liquid and Solid Samples with an Antibody Microarray Chip

    Published on: February 7, 2017

    Related Experiment Videos

    Last Updated: Jun 1, 2026

    Bacterial Gene Expression Analysis Using Microarrays
    29:41

    Bacterial Gene Expression Analysis Using Microarrays

    Published on: May 28, 2007

    DNA Microarrays: Sample Quality Control, Array Hybridization and Scanning
    09:27

    DNA Microarrays: Sample Quality Control, Array Hybridization and Scanning

    Published on: March 15, 2011

    Experimental Protocol for Detecting Cyanobacteria in Liquid and Solid Samples with an Antibody Microarray Chip
    10:57

    Experimental Protocol for Detecting Cyanobacteria in Liquid and Solid Samples with an Antibody Microarray Chip

    Published on: February 7, 2017

    Area of Science:

    • Toxicology
    • Molecular Biology
    • Biochemistry

    Background:

    • Traditional toxicology methods often lack sensitivity and specificity.
    • Emerging technologies offer new ways to assess chemical safety.

    Purpose of the Study:

    • To explore the potential of gene expression analysis in toxicology.
    • To highlight how this technology can improve safety assessments.

    Main Methods:

    • Gene expression profiling
    • Transcriptomics
    • Bioinformatics analysis

    Main Results:

    • Gene expression patterns reveal cellular responses to toxic substances.
    • Analysis provides mechanistic insights into toxicity.
    • Identifies biomarkers for early detection of adverse effects.

    Conclusions:

    • Gene expression analysis represents a significant advancement in toxicological research.
    • This technology can lead to more accurate and predictive safety evaluations.
    • It promises to transform the field of toxicology.