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Bacterial Gene Expression Analysis Using Microarrays
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Bacterial Gene Expression Analysis Using Microarrays

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Focus: DNA microarrays in toxicology

C M Henry

    Analytical Chemistry
    |June 9, 2011
    PubMed

    Abstract:

    Gene expression analysis promises to change toxicology.

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    DNA Microarrays

    Microarrays are high-throughput and relatively inexpensive assays that can be automated to analyze large quantities of data at a time. They are used in genome-wide studies to compare gene or protein expression under two varied conditions, such as healthy and diseased states. Microarrays consist of glass or silica slides on which probe molecules are covalently attached through surface functionalization. Most commonly, the slides are prepared through the chemisorption of silanes to silica...

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