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Stenotrophomonas maltophilia causing early onset neonatal sepsis

R Viswanathan1, A K Singh, C Ghosh

  • 1Department of Neonatology, Institute of Post Graduate Medical Education and Research, Kolkata, West Bengal, India. rupa_vish@rediffmail.com

Indian Pediatrics
|June 10, 2011
PubMed

Insights

Stenotrophomonas maltophilia, a multidrug-resistant bacterium, is an emerging cause of hospital-acquired infections in neonates. This report details two early-onset sepsis cases and reviews neonatal S. maltophilia infections.

Area of Science:

  • Medical Microbiology
  • Infectious Diseases
  • Neonatal Medicine

Background:

  • Stenotrophomonas maltophilia is a Gram-negative bacillus known for multidrug resistance.
  • It is an increasingly recognized nosocomial pathogen, particularly in intensive care settings.
  • Infections in the neonatal population are comparatively rare.

Observation:

  • Two cases of early-onset neonatal sepsis caused by S. maltophilia are presented.
  • The clinical presentation and management of these cases are detailed.
  • The study reviews existing literature on S. maltophilia isolation in neonates.

Findings:

  • S. maltophilia can cause severe early-onset sepsis in neonates.
  • Neonatal S. maltophilia infections, though infrequent, represent a significant clinical challenge.
  • Early diagnosis and appropriate antimicrobial therapy are crucial.

Implications:

  • Highlights the need for increased awareness of S. maltophilia as a potential neonatal pathogen.
  • Suggests that S. maltophilia should be considered in the differential diagnosis of neonatal sepsis, especially in multidrug-resistant cases.
  • Informs clinical practice regarding the management of neonatal infections caused by this resilient bacterium.

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