Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Local Anesthetics: Clinical Application as Intravenous Regional Anesthesia01:16

Local Anesthetics: Clinical Application as Intravenous Regional Anesthesia

Intravenous regional anesthesia or the Bier block technique is used to anesthetize a specific limb or extremity. It uses exsanguinated or blood-drained vessels to transport local anesthetics or LAs to the peripheral nerve trunks. Lidocaine without vasoconstrictors like epinephrine is most commonly used for this technique. Other drugs used are prilocaine, ropivacaine, and chloroprocaine. Bupivacaine is not recommended for this technique due to its high cardiac toxicity.
One of the advantages of...
Local Anesthetics: Clinical Application as Spinal Anesthesia01:11

Local Anesthetics: Clinical Application as Spinal Anesthesia

Spinal anesthetics are given during lower abdomen and limb surgeries to block sensory and motor neurons. They are administered in the mid to low lumbar regions, primarily acting on the cauda equina's nerve roots. The blockade level depends on the local anesthetic (LA) concentration. Usually, low LA concentrations are sufficient to block sensory fibers, while only high LA concentrations block motor fibers. Other factors like injection volume and speed, the patient's posture, and the drug...
Local Anesthetics: Clinical Application as Epidural Anesthesia01:29

Local Anesthetics: Clinical Application as Epidural Anesthesia

Epidural anesthetics are administered in the fat-filled epidural space, the outermost part of the spinal canal. This technique is commonly employed for pain management and anesthesia during lower abdomen and pelvis surgeries or labor and delivery.
Since epidural anesthetics can be infused through an epidural catheter, all types of drugs, including short-acting ones, can be administered. Chloroprocaine and lidocaine are examples of short and long-duration anesthetics, respectively. Bupivacaine...
Local Anesthetics: Clinical Application as Surface, Infiltration, and Conduction Block Anesthesia01:30

Local Anesthetics: Clinical Application as Surface, Infiltration, and Conduction Block Anesthesia

Depending on the target organ, local anesthetics (LAs) can be administered via various routes. In surface anesthesia, LAs are applied directly to the surface of the skin or mucous membranes. It is widely used for topical skin numbing before venipuncture or minor surgical procedures. Commonly used surface local anesthetics are lidocaine or benzocaine sprays or creams. Surface anesthesia occurs within 5 minutes and lasts for about 60 minutes. One of the main disadvantages of topical anesthesia is...
Local Anesthetics: Common Agents and Their Applications01:23

Local Anesthetics: Common Agents and Their Applications

Local anesthetics (LAs) are commonly used for various applications in medical and dental procedures. Some of the common agents used are cocaine, lidocaine, and bupivacaine.
Cocaine is an ester of benzoic acid and methylecgogine. It is used to anesthetize and vasoconstrict locally. Currently, it is used primarily for topical applications. It is beneficial for surgeries on the upper respiratory tract, providing anesthesia and shrinking the mucosa. Cocaine in the form of cocaine hydrochloride is...
Local Anesthetics: Mechanism of Action01:23

Local Anesthetics: Mechanism of Action

Local anesthetics (LAs) block sensory and motor impulses by inhibiting the sodium channels on the nerve cell membranes. This induces temporary loss of sensation, relieving pain in a specific body area.
Local anesthetics are amphiphilic molecules consisting of a hydrophobic aromatic part linked to a hydrophilic group by an ester or amide linkage. They are weak bases and are usually available as salts, which increases their solubility and stability. Once administered, LAs exist in the body either...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Regional anesthesia in the patient receiving antithrombotic or thrombolytic therapy: American Society of Regional Anesthesia and Pain Medicine Evidence-Based Guidelines (fifth edition).

Regional anesthesia and pain medicine·2025
Same author

Pain Management in Total Hip and Knee Arthroplasty: Evidence-Based and Controversial Practices in 2024.

Instructional course lectures·2025
Same author

Randomized clinical trial comparing mixed liposomal bupivacaine vs. continuous catheter for interscalene block during shoulder arthroplasty: a comparison of analgesia, patient experience, and cost.

Journal of shoulder and elbow surgery·2024
Same author

A single center descriptive study of local anesthetic dose in knee arthroplasty: Was there evidence of local anesthetic systemic toxicity?

Journal of clinical anesthesia·2024
Same author

Motor-sparing peripheral nerve blocks for hip and knee surgery.

Current opinion in anaesthesiology·2023
Same author

Spinal Versus General Anesthesia in Contemporary Revision Total Hip Arthroplasties.

The Journal of arthroplasty·2023
Same journal

Association between Ehlers-Danlos syndrome and complex regional pain syndrome: a large nationwide claims database study.

Regional anesthesia and pain medicine·2026
Same journal

Author's reply to: "Interpreting the link between vitamin D deficiency and postoperative pain after breast cancer surgery".

Regional anesthesia and pain medicine·2026
Same journal

Balancing machine learning with human application: the importance of interpretability and context.

Regional anesthesia and pain medicine·2026
Same journal

New persistent opioid use following surgery among opioid-naïve patients in the USA: a systematic review and meta-analysis of observational studies.

Regional anesthesia and pain medicine·2026
Same journal

Sensory innervation of the knee joint: a narrative review of articular branch mapping and sensory receptor distribution.

Regional anesthesia and pain medicine·2026
Same journal

Pilot study of feasibility, acceptability, and changes in clinical outcomes following a brief trauma-focused intervention for chronic pain.

Regional anesthesia and pain medicine·2026
See all related articles

Related Experiment Videos

Developing effective web-based regional anesthesia education: a randomized study evaluating case-based versus

Sandra L Kopp1, Hugh M Smith

  • 1Department of Anesthesiology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA. kopp.sandra@mayo.edu

Regional Anesthesia and Pain Medicine
|June 10, 2011
PubMed
Summary
This summary is machine-generated.

Web-based learning improved regional anesthesia knowledge, but module design and learning styles did not impact scores. Residents prefer online education but not as a replacement for lectures.

Related Experiment Videos

Area of Science:

  • Medical Education
  • Anesthesiology
  • Digital Learning

Background:

  • Web-based education offers standardized quality and multimedia integration for medical training.
  • Its role in regional anesthesia education remains largely unexplored.
  • This study investigates module design's impact on knowledge acquisition and learner preferences.

Purpose of the Study:

  • To assess if module design influences regional anesthesia knowledge acquisition.
  • To identify learner preference patterns among anesthesia residents.
  • To determine if learner preferences correlate with knowledge acquisition.

Main Methods:

  • Forty-three anesthesiology residents completed online modules (interactive case-based vs. traditional textbook-style) on regional anesthesia techniques.
  • Knowledge pre/posttests, learning style assessments, and satisfaction surveys were administered.

Main Results:

  • Residents showed improved postmodule knowledge scores for both interscalene and lumbar plexus techniques.
  • Knowledge gains were independent of module design and individual learning styles.
  • Nearly all participants favored Web-based learning but not as a replacement for lectures.

Conclusions:

  • While Web-based learning is preferred by residents, the study did not find improved learning outcomes based on module design or learning styles.
  • Educators should cautiously consider learner preferences when developing online regional anesthesia curricula.
  • The value of complex case-based modules requires further justification.