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Quantitative analysis of optic disc color.

Ungsoo Samuel Kim1, Sun Jung Kim, Seung-Hee Baek

  • 1Department of Ophthalmology, Kim's Eye Hospital, Konyang University College of Medicine, Seoul, Korea.

Korean Journal of Ophthalmology : KJO
|June 10, 2011
PubMed
Summary

ImageJ software demonstrates high reproducibility in analyzing optic disc color. The brightest cupping center

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Area of Science:

  • Ophthalmology
  • Medical Imaging
  • Image Analysis

Background:

  • Optic disc color analysis is crucial for diagnosing various ocular conditions.
  • Objective and reproducible methods are needed for accurate optic disc assessment.

Purpose of the Study:

  • To evaluate the reproducibility of ImageJ software for analyzing optic disc color.
  • To assess the inter-observer variability in optic disc measurements using ImageJ.

Main Methods:

  • 112 healthy participants underwent Kowa digital disc photography.
  • ImageJ software was used to calculate gray scales of the nasal rim (NR), brightest cupping center (BCC), and largest inferior retinal vein (IRV).
  • Three observers performed measurements three times, with reproducibility assessed by interclass correlation coefficient (ICC).
Keywords:
Gray scaleImageJOptic discReproducibility

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Main Results:

  • Good inter-observer reproducibility was found for NR (ICC=0.944), BCC (ICC=0.860), and IRV (ICC=0.789).
  • A significant age-related decrease in the gray scale of the brightest cupping center was observed (p < 0.001).
  • Mean gray scales for NR, BCC, and IRV were reported for each observer.

Conclusions:

  • ImageJ is a reproducible and objective tool for analyzing optic disc color.
  • The gray scale of the brightest cupping center diminishes with age, suggesting potential age-related changes in optic disc pigmentation.