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[Conformal stereotactic radiosurgery therapy: plan evaluation methods and results].

Péter Kovács1, Zsolt Sebestyén, Róbert Farkas

  • 1Onkoterápiás Intézet, Pécsi Tudományegyetem, Pécs, Hungary. peter.kovacs@aok.pte.hu

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Summary

This study objectively evaluated micro-multileaf collimator (mMLC)-based stereotactic radiosurgery plans. Target volume geometry significantly impacts plan conformity (COIN), but not homogeneity (HI).

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Area of Science:

  • Radiation Oncology
  • Medical Physics
  • Neurosurgery

Context:

  • Stereotactic radiosurgery (SRS) utilizes precise radiation delivery for treating brain lesions.
  • Micro-multileaf collimators (mMLCs) enable complex dose shaping in SRS.
  • Objective plan evaluation is crucial for optimizing SRS treatment outcomes.

Purpose:

  • To objectively evaluate the quality of micro-multileaf collimator (mMLC)-based stereotactic radiosurgery treatment plans.
  • To assess the influence of target volume geometrical parameters on plan quality indices.

Summary:

  • Forty-seven patients with 71 lesions underwent mMLC-based SRS using static beams.
  • Treatment plans were analyzed using conformal index (COIN), homogeneity index (HI), coverage index (CI), and healthy tissue relative overdose factor (HTOF).
  • Geometrical parameters of the target volume (lesion volume, lesion-organ distance, lesion deformity index) significantly correlated with COIN (p<0.001) but not with HI (p>0.14).

Impact:

  • Findings indicate that target volume characteristics significantly influence the conformity of mMLC-based SRS plans.
  • Homogeneity of dose distribution appears independent of target volume geometry.
  • This objective evaluation provides insights for improving SRS treatment planning and delivery.