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Treatment Resistant Cancers

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Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
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Cancer Therapies02:49

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Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
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Articles linked to this work by shared authors, journal, and citation graph.

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Patient selection for accelerated partial breast irradiation (APBI) after breast-conserving surgery: Updated evidence-based recommendations of the Groupe Européen de Curiethérapie-European Society for Therapeutic Radiology and Oncology (GEC-ESTRO) Breast Cancer Working Group.

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Treatment of Liver Metastases Using an Internal Target Volume Method for Stereotactic Body Radiotherapy
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[5th Hungarian Breast Cancer Consensus Conference - radiotherapy guidelines].

Viktor Smanykó1, Zsuzsanna Kahán2, Gabriella Gábor3

  • 1Sugárterápiás Központ, Országos Onkológiai Intézet, Budapest, Hungary. polgar.c@outlook.com.

Magyar Onkologia
|September 26, 2025
PubMed
Summary

Updated radiotherapy guidelines for breast cancer recommend its use after breast-conserving surgery for ductal carcinoma in situ and early-stage invasive cancer. Hypofractionated whole breast irradiation is an alternative to conventional treatment.

Area of Science:

  • Oncology
  • Radiotherapy
  • Breast Cancer Treatment

Background:

  • The 4th Hungarian Breast Cancer Consensus Conference revised radiotherapy guidelines based on new evidence.

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  • Radiotherapy after breast-conserving surgery (BCS) is crucial for reducing local recurrence (LR) in ductal carcinoma in situ (DCIS) and early-stage invasive breast cancer.