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Diffusion-controlled ligand binding to spheres partially covered by receptors: an effective medium treatment
1Laboratory of Chemical Physics, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892.
Abstract:
An effective medium treatment is used to extend Berg and Purcell's theory of diffusion-controlled ligand binding to a sphere partially covered by receptors. This treatment takes into account more completely the effects of interference between receptors. The results are in excellent agreement with computer simulations by Northrup.