Related Experiment Video
Updated: Jun 1, 2026
Modeling Ascending Vaginal Infection, Preterm Birth, and Neonatal Morbidity in Mice
Published on: October 10, 2025
[Proteomics and biomarkers for detection of preterm labor: a systematic review]
I Musilová1, M Kacerovský, V Tambor
1Porodnická a gynekologická klinika FN Hradec Králové.
Objective:
To review the published articles about identification of biomarkers of spontaneous preterm birth using a proteomic approach and to create a list of potential biomarkers.
Design:
Systematic review of literature.
Setting:
Department of Obstetrics and Gynecology, Medical Faculty Charles University Hradec Kralove.
Methods:
The following databases were accessed in search of relevant citation: MEDLINE, SCOPUS and PubMed. Totally 101 references were identified and relevant 37 abstracts were screened. As appropriated were pointed 16 studies. Finally, the data were extracted from five articles.
Conclusion:
The implementation of high-throughput technologies is necessary in the field of spontaneous preterm birth research. A compelling option is the use of proteomics in the area spontaneous preterm birth biomarkers identification in amniotic fluid, maternal serum/plasma, cervical-vaginal fluid and placental tissue. The data was extracted from published articles and a list of 72 proteins was created.
